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Affected parents know the drill: No sooner have their children gone back to kindergarten or in primary school after recovering from illness, they are already ill again after a short time. In contact with the environment, whether in the subway, in kindergarten or at the playground, the immature immune system is constantly faced with unknown pathogens. Therefore, children aged 1 to 8 years old suffer from an average of 5-8 common cold episodes per year, significantly more common colds than adults (2 - 3 episodes per year)1, 2).

At birth, the human immune system is not yet fully developed. In the first months of life, antibodies from the maternal immune system transmitted during pregnancy and through breastfeeding protect the new-born’s body against many diseases. This so-called "passive immunity" is lost again. During the first years of life, a child's body comes into contact with a variety of germs. In addition to the innate immune response, the adaptive immune response must now be trained. Almost everywhere there are substances that are still strange to the child's immune system. A natural environment is the best training partner. By playing outdoors, with earth and wood, by cuddling animals or through contact with other children, the immune system comes into contact with a variety of bacteria, microbes and viruses. The acquired immune response is trained and protects children effectively against new pathogens later.

Exposing the immune system to a variety of bacterial, parasitic and viral antigens in early childhood is key for the formation of a stable and healthy immune system. The far-reaching lifestyle changes in Western industrialised countries have, however, generated a germ-reduced habitat, in which the immune system encounters fewer antigens. According to the hygiene hypothesis, excessive cleanliness is partly responsible for the development of allergies and other immune diseases in which the immune system attacks normally harmless substances and sometimes its own tissues.

The hygiene hypothesis is supported by epidemiological data and scientific studies. A study showed that mice reared aseptically were much more susceptible to disease in adulthood3). The authors were of the opinion that the results are transferable to humans and concluded that there is only a small window in an early age when the immune system can be effectively trained and regulated. Early contact with various pathogens also decreases the risk of developing an allergy or falling ill. Evidence of this can be found in the "farm studies" by Prof. Dr. Erika von Mutius, Ludwig Maximilian University Munich4).

Medicianal mushrooms can train the immune system in early childhood

Beta-glucans in medicinal mushrooms such as the almond mushroom Agaricus Blazei Murill in APUXAN are able to activate the immune system and train it without causing the symptoms of disease. This means that beta-glucans are a safe dietary supplement. This makes APUXAN suitable for training the immune system, including in children*. The duration and severity of disease can be positively influenced by immune training. A relief for the whole family! The spray applicator makes APUXAN easy to use in children. The dose corresponds to the body weight of the child and is lower than in adults. For details, please read here.

* Zinc contributes to the normal function of the immune system.

1) Monto, A.S. (1994). Studies of the community and family: acute respiratory illness and infection. Epidemiol Rev 16, 351-373

2) Monto, A.S., and Ullman, B.M. (1974). Acute respiratory illness in an American community. The Tecumseh study. JAMA 227, 164-169

3) Olszak T, An D, Zeissig S, et al. Microbial Exposure During Early Life Has Persistent Effects on Natural Killer T Cell Function. Science (New York, NY). 2012;336(6080):489-493. doi:10.1126/science.1219328

4) Mutius, E. (2007). Allergies, infections and the hygiene hypothesis--the epidemiological evidence. Immunobiology 212, 433-439